Reinventing the discovery, development, and commercialization of new medicines
We develop transformative medicines and technologies by building agile, focused companies called Vants.
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20+
subsidiary companies built
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08
successful Phase 3 trials of 9 total
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06
FDA approvals
Our model aligns incentives to drive fast, high-quality execution and rigorous capital allocation.
We employ technology across discovery, development, and commercialization.
Dermavant
Leading innovation in medical dermatology
Immunovant
Advancing potentially transformative therapies for autoimmune diseases
Genevant
Delivering results through nucleic acids
Designing Better Molecules, Atom by Atom
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Modalities
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Platforms
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Recent Publications
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Modalities
Heterobifunctionals
We have built an end-to-end platform for heterobifunctional degrader discovery which we are expanding to other chemically-induced proximity applications. Learn more.
Covalency
We’re expanding the druggable proteome and unlocking the next generation of high value small molecule therapeutics. Learn more.
Designing Best-in-Class Small Molecules
Our computation-first approach is used to design molecules that rapidly reach the desired TPP for disease areas where effective therapeutic solutions are lacking. Learn more.
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Platforms
Our discovery computational platform, QUAISAR (QUantum, AI, and Structure-Activity Relationships) is leveraged to gain critical project insights and desired properties for drug engineering.
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Recent Publications
Rigorous Free Energy Simulations in Virtual Screening
Virtual high throughput screening (vHTS) in drug discovery is a power approach to identify hits: when applied successfully, it can be much faster and cheaper than experimental high-throughput screening approaches. However, mainstream vHTS tools have significant limitations: ligand-based methods depend on knowledge of existing chemical matter, while structure-based tools such as docking involve...
Read MoreLearn About Our Science
Advancing medicines that matter
View our broad and differentiated pipeline of investigational drugs.
Learn more about our work
Advancing medicines that matter
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View our broad and differentiated pipeline of investigational drugs.